Epithalon 10mg
Longevity
$109
Tetrapeptide developed by the St. Petersburg Institute of Bioregulation that activates telomerase, lengthens telomeres, and regulates the pineal gland for anti-aging effects.
Overview
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It activates telomerase in somatic cells, elongating telomeres and potentially extending cellular lifespan. Human trials spanning 12+ years have reported improvements in melatonin secretion, immune function, and reduced mortality in elderly cohorts.
Lab Results — 10mg
Every batch is independently tested. Results below are from the Certificate of Analysis for the 10mg batch.
Scientific Details
Molecular Formula
C₁₄H₂₂N₄O₉
Molecular Weight
390.3 g/mol
Form
Lyophilized tetrapeptide powder
Solubility
Freely soluble in water
Dosage Range
5–10mg daily for 10–20 day cycles (research context)
Plasma Half-Life
~2 hours
Bioavailability
~80% subcutaneous
Resources
Key peer-reviewed studies supporting the efficacy and safety of this compound.
Peptide regulation of aging
Khavinson V.K. — Neuroendocrinology Letters (2002)
Key FindingEpithalon restored melatonin secretion and improved antioxidant status in elderly patients over a 12-year follow-up study.
Epithalon activates telomerase and elongates telomeres in human cells
Khavinson V. et al. — Bulletin of Experimental Biology and Medicine (2003)
Key FindingEpithalon induced telomerase activity in human somatic cells and produced measurable telomere elongation after treatment.
Effect of Epithalon on mortality of elderly cohort
Anisimov V.N. et al. — Gerontology (2003)
Key FindingEpithalon treatment in elderly subjects was associated with a statistically significant reduction in all-cause mortality over a 6-year observation period.