Noopept 10mg
Cognitive
$69
Dipeptide nootropic that enhances memory consolidation, upregulates NGF and BDNF expression, and provides neuroprotection against oxidative and excitotoxic damage.
Overview
Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a synthetic dipeptide nootropic developed in Russia and reported to be 1,000 times more potent than piracetam by weight. It is a prodrug for cycloprolylglycine, an endogenous neuropeptide that modulates AMPA receptors. Noopept upregulates NGF and BDNF expression, enhances alpha and beta brain wave activity, and provides neuroprotection against glutamate excitotoxicity and oxidative stress.
Lab Results — 10mg
Every batch is independently tested. Results below are from the Certificate of Analysis for the 10mg batch.
Scientific Details
Molecular Formula
C₁₇H₂₂N₂O₄
Molecular Weight
318.4 g/mol
Form
Lyophilized powder
Solubility
Soluble in water and ethanol
Dosage Range
10–30mg daily (research context)
Plasma Half-Life
~30–60 minutes
Bioavailability
~99% intranasal; ~100% sublingual
Resources
Key peer-reviewed studies supporting the efficacy and safety of this compound.
Noopept stimulates NGF and BDNF expression in rat hippocampus
Ostrovskaya R.U. et al. — Bulletin of Experimental Biology and Medicine (2008)
Key FindingNoopept significantly increased NGF and BDNF mRNA levels in rat hippocampus and cortex after 28 days of administration.
Noopept and cognitive function in patients with mild cognitive impairment
Neznamov G.G. & Teleshova E.S. — Neuroscience and Behavioral Physiology (2009)
Key FindingNoopept improved memory, attention, and cognitive performance in a randomized controlled trial of patients with mild cognitive impairment.
Neuroprotective effects of Noopept against glutamate excitotoxicity
Gudasheva T.A. et al. — European Journal of Pharmacology (1996)
Key FindingNoopept protected cortical neurons against glutamate-induced excitotoxicity and reduced lipid peroxidation markers in neuronal cultures.