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Selank
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Selank 5mg

Cognitive

$89

4.0 (24 reviews)

Anxiolytic peptide analog of tuftsin that modulates GABAergic tone, stabilizes enkephalins, and reduces anxiety without sedation or dependence.

5mg per vial, lyophilized powder
Tuftsin analog heptapeptide
Third-party tested for purity and potency
Intranasal or subcutaneous administration
1
Third-party tested

Overview

Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin, developed at the Institute of Molecular Genetics in Moscow. Approved in Russia as an anxiolytic and nootropic, it reduces anxiety and improves stress resilience without the sedation, tolerance, or withdrawal associated with benzodiazepines. It simultaneously upregulates BDNF and modulates monoamine neurotransmitter systems.

Lab Results — 5mg

Every batch is independently tested. Results below are from the Certificate of Analysis for the 5mg batch.

Test
Result
Status
Identity (HPLC-MS)
Confirmed Selank
Pass
Purity
99.0%
Pass
Heavy Metals (Pb)
< 0.05 ppm
Pass
Endotoxin (LAL)
< 1 EU/mg
Pass
Residual Solvents
Not detected
Pass

Scientific Details

Molecular Formula

C₃₃H₅₇N₁₁O₉

Molecular Weight

751.9 g/mol

Form

Lyophilized peptide powder

Solubility

Soluble in sterile water or saline

Dosage Range

250–500mcg daily intranasal (research context)

Plasma Half-Life

~20 minutes (plasma); prolonged CNS effects

Bioavailability

~92% intranasal

Resources

Key peer-reviewed studies supporting the efficacy and safety of this compound.

Selank as an anxiolytic peptide

Semenova T.P. et al.Bulletin of Experimental Biology and Medicine (2010)

Key FindingSelank produced anxiolytic effects comparable to diazepam in animal models without motor impairment, sedation, or tolerance development.

Effects of Selank on serotonin metabolism

Nadorova A.V. et al.Doklady Biochemistry and Biophysics (2016)

Key FindingSelank normalized serotonin transporter gene expression and increased serotonin turnover in stressed rats.

Immunomodulatory and nootropic properties of Selank

Zozulya A.A. et al.CNS Drug Reviews (2006)

Key FindingSelank exhibited dual anxiolytic and cognitive-enhancing properties in clinical trials, with an excellent tolerability profile and no withdrawal effects.