Sermorelin 10mg
Performance
$79
Synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary to produce and secrete GH naturally, supporting body composition, recovery, and sleep.
Overview
Sermorelin (GRF 1-29 NH2) is a synthetic analog of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It stimulates the pituitary somatotroph cells to produce and release GH in a physiological pulsatile pattern, preserving the natural GH-IGF-1 axis feedback mechanism. It was FDA-approved for pediatric GH deficiency and is widely studied for adult hormone optimization.
Lab Results — 10mg
Every batch is independently tested. Results below are from the Certificate of Analysis for the 10mg batch.
Scientific Details
Molecular Formula
C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular Weight
3,357.9 g/mol
Form
Lyophilized peptide powder
Solubility
Soluble in bacteriostatic water
Dosage Range
200–500mcg before bed (research context)
Plasma Half-Life
~10–20 minutes
Bioavailability
~90% subcutaneous
Resources
Key peer-reviewed studies supporting the efficacy and safety of this compound.
Sermorelin: a better approach to management of adult-onset GH insufficiency?
Walker R.F. — Clinical Interventions in Aging (2006)
Key FindingSermorelin restored physiological GH pulsatility in GH-deficient adults and improved body composition, sleep quality, and energy levels.
GHRH analog effects on body composition in aging adults
Corpas E. et al. — Journal of Clinical Endocrinology & Metabolism (1992)
Key FindingSermorelin increased GH and IGF-1 levels and improved lean mass in elderly men while maintaining physiological feedback regulation.
Effects of growth hormone-releasing hormone on sleep and cognition
Perras B. et al. — Journal of Sleep Research (1999)
Key FindingGHRH administration enhanced slow-wave sleep and improved declarative memory consolidation in healthy older adults.